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Korean Journal of Schizophrenia Research 2006;9(1):31-34.
정신분열병 임산부에서 Transcranial Magnetic Stimulation의 부가치료 효과
Hyun-Seok Choi, MD and Yong-Ku Kim, MD, PhD
Objectives:Since any antipsychotics have not been warranted to be totally safe for the developing fetus, pharmacotherapeutic treatments for pregnant schizophrenic patients need cautious consideration. Alternately, somatic treatment such as TMS may be also an alternative treatment for the pregnant schizophrenic patients. We report the effect of rTMS as the adjuvant treatment to risperidone in the pregnant schizophrenic patients.
Methods:rTMS was applied to a pregnant schizophrenic woman after maintaining of risperidone 3 mg for 2 weeks. The patient was received high frequency (10 Hz) on left dorsolateral prefrontal cortex for 10 min and subsequently low frequency (1 Hz) on left temporal lobe for 10 min. rTMS was applied totally 18,000 Hz for 15 days. PANSS, CDSS was measured at baseline, week 1, week 2, week 3 and neurocognitive test was applied before rTMS and at week 4 after rTMS.
Results:The PANSS total score and CDSS symptoms were decreased after rTMS while positive and negative symptoms were not decreased.
Conclusion:This case suggests TMS may also be an adjuvant strategy in treating pregnant schizophrenic patients. (Korean J Schizophr Res 2006;9:31-34)
Key Words: Association study,Schizophrenia,Single nucleotide polymorphism
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