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Korean J Schizophr Res > Volume 19(2); 2016 > Article
Korean Journal of Schizophrenia Research 2016;19(2):60-67.
DOI: https://doi.org/10.16946/kjsr.2016.19.2.60    Published online October 31, 2016.
Prevalence of Sexual Dysfunction in Schizophrenic Patients Taking Antipsychotic Drugs.
Sun Hwa Jeong, Shi Hyun Kang, Dong Yeon Park, Hai Joo Yoon, Eun Kyung Park, Jong Il Lee
1Department of Psychiatry, National Center for Mental Health, Seoul, Korea. lji7542@naver.com
2Department of Clinical Psychology, National Center for Mental Health, Seoul, Korea.
3Department of Clinical Trial Center, National Center for Mental Health, Seoul, Korea.
Sexual dysfunction is said to affect the compliance of drug and quality of life. This study is a research to investigate the prevalence of sexual dysfunction and affecting factors that can occur when schizophrenic and schizoaffective patients have taken drugs.
Subjects were 300 patients who have been taken inpatient or outpatient treatment in national seoul hospital. We used UKU-S, ASEX scale for evaluating the prevalence of sexual dysfunction and CGI-S, PANSS negative scale and CES-D for investigating the influence of psychopathology and depressive symptoms on sexual dysfunction.
It was reported sexual dysfunction 82.7% in male and 92.2% in female with 7 items of UKU-S. The prevalence of sexual dysfunction with criteria of ASEX was 47.72% in male and 65.05% in female. Sexual dysfunction was more prevalent in patients taking prolactin-elevation drugs. In the factor analysis for the sexual dysfunction it was investigated that age, onset time, CGI-S, PANSS negative scale, and CES-D can affect the sexual dysfunction in both male and female.
This study reported that many patients complained of sexual dysfunction. On considering the influence of sexual dysfunction to compliance and quality of life, clinicians evaluate sexual side effects more actively because patients are more likely not spontaneously tell the sexual side effects in comparison to others.
Key Words: Sexual dysfunction · Schizophrenia · Antipsychotic agent
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