Prevalence of the Metabolic Syndrome among Outpatients with Schizophrenia or Schizoaffective Disorder.

Lee, Hwa Young; Choi, Jung Eun

doi:2012.15.1.39

Korean J Schizophr Res > Volume 15(1); 2012 > Article

Original Article

Korean Journal of Schizophrenia Research 2012;15(1):39-45.
DOI: https://doi.org/10.16946/kjsr.2012.15.1.39 Published online June 30, 2012.

Prevalence of the Metabolic Syndrome among Outpatients with Schizophrenia or Schizoaffective Disorder.

Hwa Young Lee, Jung Eun Choi

Department of Psychiatry, Seoul Metropolitan Eunpyeong Hospital, Seoul, Korea. jeweleye@seoul.go.kr

Abstract

OBJECTIVES
The aim of this study were to assess a) the prevalence of metabolic syndrome in outpatients with schizophrenia or schizoaffective disorder, b) the comparison of characteristics of patients with or without the metabolic syndrome, c) the sensitivity, specificity and positive predictive values of individual criteria for metabolic syndrome.
METHODS
This study assessed the prevalence of the metabolic syndrome among 128 schizophrenia or schizoaffective disorder patients using the National Cholesterol Education Program-Adult Treatment Panel III.
RESULTS
Of patients, 54.7% (M : 49.3%, F : 61.4%) had metabolic syndrome. The metabolic syndrome was associated with medical history of diabetes, hypertension and dyslipidemia. Presence of abdominal obesity was most sensitive (97.1%), while raised fasting glucose was most specific (89.7%). Combining abdominal obesity/raised triglycerides and abdominal obesity/low HDL cholesterol had 100% sensitivity.
CONCLUSION
The metabolic syndrome is highly prevalent among outpatients with schizophrenia or schizoaffective disorder. This study suggests that the measurement of abdominal obesity is a simple test to identify individuals at high risk for metabolic syndrome.

Key Words: Schizophrenia · Schizoaffective disorder · Metabolic syndrome · Prevalence